MBCP™: Synthetic Bone Graft Substitute Bioactive Calcium Phosphate
Ideally, any biocompatible synthetic bone graft substitute material used to replace or augment graft material should become integrated with the surrounding bone tissue and ultimately be replaced by new healthy bone, as seen with autologous graft.
MBCP™ is a biphasic calcium phosphate synthetic bone graft substitute with a unique micro and macroporous structure that most closely resembles to the architecture of natural human bone. Soluble and resorbable, it gradually dissolves in the body, promoting new bone formation through the release of calcium and phosphate ions. In time, the porous structure becomes completely infiltrated with, and replaced by, healthy viable bone.
MBCP™ Technology’s Key Features
Provides a matrix for new bone growth
HA alone resorbs too slowly while TCP resorbs too fast. Bi-phasic HA and TCP allow for a resorption rate similar to that of human bone
Interconnected network of macropores and micropores that enables the colonization of bone cells and biological fluid uniformly within the matrix
For ionic exchange: TCP dissolution and bone crystal precipitation creare newly bioactive interface with bone cells
Macropores are a network of interconnected spaces that promote the biological infiltration and cellular colonization by osteoblasts and osteoclasts
Micropores are the intercrystalline spaces where dissolution and recrystallisation occurs
Host bone formation is demonstrated