Description
- Tissue origin :
Apatos Cortical: heterologous cortical bone - Tissue collagen :
Degraded - Physical form :
Radiopaque granules of mineral hydroxyapatite - Composition :
Apatos Cortical: 100% cortical bone - Granulometry :
600-1000 µm - Re-entry time :
About 5 months - Packaging :
Cortical | Vial: 0.5 g, 1.0 g
Characteristics
- Apatos is a biocompatible¹, osteoconductive² biomaterial of heterologous origin with characteristics similar to mineralized human bone³ ⁴; it can therefore be used as an alternative to autologous bone. The natural microporous consistency of Apatos facilitates the formation of new bone tissue in bone defect area⁵, accelerating the process. Apatos nanocrystalline hydroxyapatite is available in cortical and mixed granules.
- Handling
- Apatos must always be hydrated and thoroughly mixed with a few drops of sterile saline; it can also be mixed with patient’s blood. Finally it can be mixed if necessary with the drug selected for surgery; the mixture thus obtained should be positioned with a sterile spatula or syringe for biomaterials.
- Clinical indications
- Apatos is a universal filler, that can be used to treat peri-implant defects and two-wall defects⁶ ⁷. Because of its granulometry, Apatos cannot be used in narrow defects, but it fits well in big sockets, e.g. after molar extractions. Both types of sinus lift (with crestal or lateral access)⁴ ⁸ can be performed with Apatos as bone substitute, as well as surgeries for horizontal regenerations. Apatos Cortical is characterized by a very long resorption time, guaranteeing optimal preservation of the graft volume. When needed, Apatos grafts can be protected with OsteoBiol® Evolution membrane or stabilized with Cortical Lamina.
Indications:
Alveolar regeneration / Dehicences and fenestrations / Lateral access sinus lift
Oral surgery: granulomas, dentigerous cysts and split crests.
- Bibliography
- ¹ TRUBIANI O, SCARANO A, ORSINI G, DI IORIO D, D’ARCANGELO C, PICCIRILLI M, SIGISMONDO M, CAPUTI S
THE PERFORMANCE OF HUMAN PERIODONTAL LIGAMENT MESENCHYMAL STEM CELLS ON XENOGENIC BIOMATERIALS
INT J IMMUNOPATHOL PHARMACOL, 2007 JAN-MAR; 20(1 SUPPL 1):87-91² BRUNELLI G, SOLLAZZO V, CARINCI F, PALMIERI A, GIRARDI A, MONGUZZI R
OSTEOBIOL® INFLUENCES OSTEOGENIC DIFFERENTIATION OF ADIPOSE DERIVED STEM CELLS
EUR J INFLAMM, 2011, VOL. 9, NO. 3(S), 103-107³ ORSINI G, SCARANO A, PIATTELLI M, PICCIRILLI M, CAPUTI S, PIATTELLI A
HISTOLOGIC AND ULTRASTRUCTURAL ANALYSIS OF REGENERATED BONE IN MAXILLARY SINUS AUGMENTATION USING A PORCINE BONE-DERIVED BIOMATERIAL
J PERIODONTOL 2006 DEC;77(12):1984-90⁴ SCARANO A, PIATTELLI A, PERROTTI V, MANZON L, IEZZI G
MAXILLARY SINUS AUGMENTATION IN HUMANS USING CORTICAL PORCINE BONE: A HISTOLOGICAL AND HISTOMORPHOMETRICAL EVALUATION AFTER 4 AND 6 MONTHS
CLIN IMPLANT DENT RELAT RES, 2011 MAR; 13(1):13-18⁵ IEZZI G, DEGIDI M, PIATTELLI A, MANGANO C, SCARANO A, SHIBLI JA, PERROTTI V
COMPARATIVE HISTOLOGICAL RESULTS OF DIFFERENT BIOMATERIALS USED IN SINUS AUGMENTATION PROCEDURES: A HUMAN STUDY AT 6 MONTHS
CLIN ORAL IMPLANTS RES, 2012 DEC;23(12):1369-76 EPUB 2011 NOV 2⁶ BARONE A, AMERI S, COVANI U
IMMEDIATE POSTEXTRACTION IMPLANTS: TREATMENT OF RESIDUAL PERI-IMPLANT DEFECTS. A RETROSPECTIVE ANALYSIS
EUR J IMPLANT PROSTHODONTICS, 2006,2: 99-106⁷ BARONE A, TOTI P, QUARANTA A, DERCHI G, COVANI U
THE CLINICAL OUTCOMES OF IMMEDIATE VERSUS DELAYED RESTORATION PROCEDURES ON IMMEDIATE IMPLANTS: A
COMPARATIVE COHORT STUDY FOR SINGLE-TOOTH REPLACEMENT
CLIN IMPLANT DENT RELAT RES, 2014 MAY 22 EPUB AHEAD OF PRINT⁸ SCARANO A, PIATTELLI A, ASSENZA B, QUARANTA A, PERROTTI V, PIATTELLI M, IEZZI G
PORCINE BONE USED IN SINUS AUGMENTATION PROCEDURES: A 5-YEAR RETROSPECTIVE CLINICAL EVALUATION
J ORAL MAXILLOFAC SURG, 2010 AUG; 68(8):1869-73
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